Anti-inflammatory effects of flap and lymph node transfer.
Identifieur interne : 002138 ( Main/Exploration ); précédent : 002137; suivant : 002139Anti-inflammatory effects of flap and lymph node transfer.
Auteurs : Tiina P. Viitanen [Finlande] ; Mikko T. Visuri [Finlande] ; Eeva Sulo [Finlande] ; Anne M. Saarikko [Finlande] ; Pauliina Hartiala [Finlande]Source :
- The Journal of surgical research [ 1095-8673 ] ; 2015.
Descripteurs français
- KwdFr :
- Aisselle, Cytokines (métabolisme), Exsudats et transsudats (métabolisme), Facteur de croissance endothéliale vasculaire de type C (métabolisme), Facteur de croissance endothéliale vasculaire de type D (métabolisme), Femelle, Humains, Inflammation (métabolisme), Lambeaux chirurgicaux, Lymphadénectomie, Lymphoedème (), Mammoplastie, Noeuds lymphatiques (transplantation), Plaies et blessures (métabolisme).
- MESH :
- métabolisme : Cytokines, Exsudats et transsudats, Facteur de croissance endothéliale vasculaire de type C, Facteur de croissance endothéliale vasculaire de type D, Inflammation, Plaies et blessures.
- Aisselle, Femelle, Humains, Lambeaux chirurgicaux, Lymphadénectomie, Lymphoedème, Mammoplastie, Noeuds lymphatiques.
English descriptors
- KwdEn :
- Axilla, Cytokines (metabolism), Exudates and Transudates (metabolism), Female, Humans, Inflammation (metabolism), Lymph Node Excision, Lymph Nodes (transplantation), Lymphedema (prevention & control), Mammaplasty, Surgical Flaps, Vascular Endothelial Growth Factor C (metabolism), Vascular Endothelial Growth Factor D (metabolism), Wounds and Injuries (metabolism).
- MESH :
- chemical , metabolism : Cytokines, Vascular Endothelial Growth Factor C, Vascular Endothelial Growth Factor D.
- metabolism : Exudates and Transudates, Inflammation, Wounds and Injuries.
- prevention & control : Lymphedema.
- transplantation : Lymph Nodes.
- Axilla, Female, Humans, Lymph Node Excision, Mammaplasty, Surgical Flaps.
Abstract
Transfer of healthy tissue is commonly used in the treatment of complicated wounds and in reconstruction of tissue defects. Recently, microvascular lymph node transfer (LN) has been used to improve the lymphatic function in lymphedema patients. To elucidate the biological effects of flap transfer (with and without lymph nodes), we have studied the postoperative production of proinflammatory, anti-inflammatory, prolymphangiogenic and antilymphangiogenic cytokines, and growth factors (interleukin 1α [IL-1α], IL-1β, tumor necrosis factor α [TNF-α], IL-10, transforming growth factor β1 [TGF-β1], IL-4 and IL-13, and vascular endothelial growth factor C [VEGF-C] and VEGF-D) in postoperative wound exudate samples.
DOI: 10.1016/j.jss.2015.04.041
PubMed: 26013441
Affiliations:
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Electronic address: pauliina.hartiala@tyks.fi.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Plastic and General Surgery, Turku University Hospital, Turku, Finland; Department of Medical Microbiology and Immunology, University of Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author></analytic><series><title level="j">The Journal of surgical research</title><idno type="eISSN">1095-8673</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Axilla</term><term>Cytokines (metabolism)</term><term>Exudates and Transudates (metabolism)</term><term>Female</term><term>Humans</term><term>Inflammation (metabolism)</term><term>Lymph Node Excision</term><term>Lymph Nodes (transplantation)</term><term>Lymphedema (prevention & control)</term><term>Mammaplasty</term><term>Surgical Flaps</term><term>Vascular Endothelial Growth Factor C (metabolism)</term><term>Vascular Endothelial Growth Factor D (metabolism)</term><term>Wounds and Injuries (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Aisselle</term><term>Cytokines (métabolisme)</term><term>Exsudats et transsudats (métabolisme)</term><term>Facteur de croissance endothéliale vasculaire de type C (métabolisme)</term><term>Facteur de croissance endothéliale vasculaire de type D (métabolisme)</term><term>Femelle</term><term>Humains</term><term>Inflammation (métabolisme)</term><term>Lambeaux chirurgicaux</term><term>Lymphadénectomie</term><term>Lymphoedème ()</term><term>Mammoplastie</term><term>Noeuds lymphatiques (transplantation)</term><term>Plaies et blessures (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Cytokines</term><term>Vascular Endothelial Growth Factor C</term><term>Vascular Endothelial Growth Factor D</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Exudates and Transudates</term><term>Inflammation</term><term>Wounds and Injuries</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cytokines</term><term>Exsudats et transsudats</term><term>Facteur de croissance endothéliale vasculaire de type C</term><term>Facteur de croissance endothéliale vasculaire de type D</term><term>Inflammation</term><term>Plaies et blessures</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="transplantation" xml:lang="en"><term>Lymph Nodes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Axilla</term><term>Female</term><term>Humans</term><term>Lymph Node Excision</term><term>Mammaplasty</term><term>Surgical Flaps</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Aisselle</term><term>Femelle</term><term>Humains</term><term>Lambeaux chirurgicaux</term><term>Lymphadénectomie</term><term>Lymphoedème</term><term>Mammoplastie</term><term>Noeuds lymphatiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Transfer of healthy tissue is commonly used in the treatment of complicated wounds and in reconstruction of tissue defects. Recently, microvascular lymph node transfer (LN) has been used to improve the lymphatic function in lymphedema patients. To elucidate the biological effects of flap transfer (with and without lymph nodes), we have studied the postoperative production of proinflammatory, anti-inflammatory, prolymphangiogenic and antilymphangiogenic cytokines, and growth factors (interleukin 1α [IL-1α], IL-1β, tumor necrosis factor α [TNF-α], IL-10, transforming growth factor β1 [TGF-β1], IL-4 and IL-13, and vascular endothelial growth factor C [VEGF-C] and VEGF-D) in postoperative wound exudate samples.</div></front></TEI><affiliations><list><country><li>Finlande</li></country><region><li>Finlande occidentale</li></region><settlement><li>Turku</li></settlement></list><tree><country name="Finlande"><region name="Finlande occidentale"><name sortKey="Viitanen, Tiina P" sort="Viitanen, Tiina P" uniqKey="Viitanen T" first="Tiina P" last="Viitanen">Tiina P. Viitanen</name></region><name sortKey="Hartiala, Pauliina" sort="Hartiala, Pauliina" uniqKey="Hartiala P" first="Pauliina" last="Hartiala">Pauliina Hartiala</name><name sortKey="Saarikko, Anne M" sort="Saarikko, Anne M" uniqKey="Saarikko A" first="Anne M" last="Saarikko">Anne M. Saarikko</name><name sortKey="Sulo, Eeva" sort="Sulo, Eeva" uniqKey="Sulo E" first="Eeva" last="Sulo">Eeva Sulo</name><name sortKey="Visuri, Mikko T" sort="Visuri, Mikko T" uniqKey="Visuri M" first="Mikko T" last="Visuri">Mikko T. Visuri</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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